The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
ApoE Monoclonal Antibody
详细信息
| 交叉反应性 | 人 |
| 应用 | WB; IHC; IF; FCM; ELISA |
| 分子量(DA) | 72kDa-95kDa |
| 免疫原 | Synthesized peptide derived from the Internal region of h... |
| 来源 | Monoclonal, Mouse,IgG |
| 组成(Formulation) | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02%... |
| 稀释比例 | WB: 1/500-1/2000; IHC: 1/200-1/1000; Flow cytometry: 1/20... |
| 纯化工艺(Immunogen) | The antibody was affinity-purified from mouse antiserum b... |
| 浓度 | 1 mg/ml |
| 功能 | disease:Defects in APOE are a cause of hyperlipoproteinem... |
| 基因名称(Gene Name) | APOE |
| 其他名称 | APOE; Apolipoprotein E; Apo-E |
| 保存方式 | Store at -20℃. Avoid freeze-thaw cycles, Prepare working ... |
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背景信息
货号:ZJ-B25010212
20ul
¥460
50ul
¥945
100ul
¥1350
货期:
3个工作日